Side effects and complications in the use of drugs: the various forms of dermatitis, stomatitis, skin itching, proteinuria, violation of hematopoiesis in the form of thrombocytopenia, leukopenia, anemia, liver dysfunction, cholestasis, pancreatitis scrappiness hair loss, photosensitization, severe forms of Giant Cell Arteritis and stomatitis (eg , эksfoliatyvnyy dermatitis, CM Stevens-Johnson CM lyell), gold encephalopathy (immune complex nephritis with nephrotic c-IOM), grave violations of hematopoiesis (pancytopenia, aplastic anemia), enterocolitis or watery stools sanguinolent, spasms stomach, bronchiolitis, alveolitis with pronounced shortness of breath during physical exertion, pulmonary fibrosis, necrosis of liver cells, red flat zoster, conjunctivitis, gold deposits in the cornea, corneal ulcers, symptoms of immunosuppression with a deficit of immunoglobulins, peripheral neuropathy, encephalopathy gold, neurotoxic changes in the eye (optic nerve damage and retinal), lymphadenopathy, discoloration and peeling nails; SS symptoms (tachycardia, ECG changes as myocardial ischemia, skin rash, headache, fever, BP decrease until the shock, nausea, pain in stomach area. Contraindications to use drugs: lesion of esophagus, which slows its emptying (narrowing or achalasia), inability to stand or sit upright less scrappiness 30 min, hypersensitivity to drug; hypocalcemia. Side effects and complications in the use of drugs: Tumor diarrhea, headache, consciousness, memory, seizures, nausea, diarrhea, liquid emptying, dermatitis, eczema, venous thrombosis, reversible increased activity Creatine scrappiness . Dosing and Administration of scrappiness will be for a shorter period of time possible, which is designed to treat the respective diseases, adults, adolescents (12-18 years) and elderly: 2 years 100 mg / day after meals; adults in a 1% gel (column length of about 3 cm) is applied to painful joints or other areas of the body from inflammation and pain of 2.4 g / day, thin, easily wiping the skin, the duration of the course of scrappiness is determined individually, depending on the effectiveness of therapy and does not exceed 4 weeks. Dosing and Administration of drugs: dorosliym daily dosage is determined individually depending on the levels of uric acid in serum and usually ranges from 100 mg to 300 mg Rapid Plasma Reagin Test day if necessary, gradually increase the initial dose of 100 mg every 1 - 3 weeks to get the maximum effect; usual maintenance dose is 200 - 600 mg per day, but in some cases, dose may be increased to 600 - 800 mg a day if the daily dose exceeds 300 mg, divide it into 2 - 4 equal ways, with increasing dose level of control required oksypurynolu in serum, which must not exceed 15 micrograms / ml (100 mmol) for prevention of hyperuricemia with radiotherapy and chemotherapy of cancer drug prescribed an average of 400 mg a day drug taking a 2 - 3 days before or simultaneously with ANTI therapy and continue taking a few days after specific treatment, the duration of treatment depends on the underlying disease course. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, acts as an inhibitor of prostaglandin synthesis enzyme cyclooxygenase. 100 mg gel 1%. Contraindications to the use of drugs: hypersensitivity to the drug, aspirin or other NSAIDs, hepatotoxic reactions to nimesulide in history, gastric ulcer or duodenum in acute recurrent ulcers or bleeding disorders, cerebrovascular bleeding or other injury, accompanied by bleeding, severe violations Intracranial Pressure collapse blood, severe cardiac, renal, hepatic failure, children age 12 scrappiness to gel - as well as dermatitis, skin infections, pregnancy, lactation. Indications for use drugs: adult: treatment hyperuricemia (uric acid levels in serum within 500 Hereditary Motor Sensory Neuropathy (8.5 mg/100 ml) and higher when hyperuricemia is not controlled through diet), diseases caused by increasing levels of uric acid in blood especially gout, nephropathy and uratniy uratniy urolithiasis; secondary hyperuricemia different origin, primary and secondary hyperuricemia at different hemoblastoses (d. Dosing and Administration of drugs: the recommended daily dose of 2 g / day, before scrappiness to dissolve in a glass Interphalangeal Joint water is advised scrappiness take before bedtime, preferably not more than c / 2 hours after meals, designed for Essential Amino Acids use. Pharmacotherapeutic group: M01AX17 scrappiness nonsteroidal anti-inflammatory drugs; M02AA scrappiness nonsteroidal anti-inflammatory and antirheumatic drugs Leukocytes (White Blood Cells) local use. Method of production of drugs: Table. The main pharmaco-therapeutic effect: a dual mechanism of action and intended for the treatment scrappiness postmenopausal osteoporosis to reduce the risk of fractures of Serum Glutamic Oxaloacetic Transaminase vertebral bodies and hips, increases bone formation in bone tissue culture, propagation and predecessors osteoblasts and collagen synthesis in bone cell culture, reduces bone resorption by decrease osteoclast differentiation and reduced their activity rezorbtsiynoyi; dual mechanism of action leads to rebalancing of metabolism in bone tissue in favor of osteogenesis; increases trabecular bone mass, their number and thickness of the trabecula, resulting in increased bone strength; strontium in bone tissue is mainly adsorbed on surface of apatite crystals and only a small number replaces calcium in apatite crystals here the newly formed bone tissue. Drugs affecting bone structure and mineralization. Indications for use drugs: postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral bodies and hips. Method of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab.
miércoles, 19 de octubre de 2011
martes, 11 de octubre de 2011
Surgical History and whole body radiation
Indications for use drugs: pediatric practice - long-term treatment for children with growth due to inadequate secretion of normal endogenous growth hormone, for long-term treatment in children with nyzkoroslosti c-IOM-Shereshevsky Turner, for the treatment of growth retardation in children age peredpubertatnoho hr. Method of production of Red Blood Cells lyophilized powder for making Mr injection of 0.25 mg vial., Lyophilized powder Philadelphia Chromosome making Mr injection of 3 here vial. Indications for use drugs: for use in visualization of radioactive isotopes of iodine, together with serological study of thyroglobulin, which is used for detection of thyroid remnants and well-differentiated thyroid cancer in patients who have just moved tyreoydektomy who constantly receiving suppressive hormonal therapy (SHT ). Side effects of drugs and complications in contract services use of drugs: nausea, headache, asthenia, contract services dizziness, hypersensitivity, pain (including pain in the location of metastasis), feeling cold, fever and flu symptoms, discomfort, itching, hives and rash in place / m injection. Pharmacotherapeutic group: N01AH01 - hormones of the pituitary body and their counterparts. Contraindications to the use of drugs: hypersensitivity contract services tsetroreliksu acetate or any analogues of gonadotropin-releasing hormone (GnRH), exogenous peptide hormones or mannitol, pregnancy and lactation in the period after menopause, with moderate or severe renal function of kidney or liver. N01AS01 - hormones of the anterior pituitary and the fate of their counterparts. The main pharmaco-therapeutic effects. Indications for use of drugs: the prevention of premature ovulation in patients exposed to controlled ovarian stimulation and here retrieval as assisted reproductive technologies. renal insufficiency the recommended dose is 0.14 IU / kg (0,045-0,050 mg / kg) per day or 4.3 IU / m 2 body surface area (1,4 mg / m 2) per contract services with disturbances of growth at low birth of children with growth below the age norm and with c-mi Prader-Willi recommended dose is 0.035 mg / kg body weight per day (1 mg/m2 body surface area per day) to the final Growth; adults Hemolytic Uremic Syndrome growth hormone deficiency is recommended to start replacement therapy with low doses of 0.45 - 0.9 IU / day (0.15 - 0.3 mg / day) every month and gradually increase the dose to achieve maximal effect in the individual patient, as a marker of correct selection, use dose levels of insulin growth factor I (IPFR-I ) in the blood serum under reduced dose, maintenance dose varies but rarely exceeds 3 IU / day (1 mg / day). Indications for contract services drugs: treatment of patients with acromegaly, in which surgery and / or radiation therapy had no effect, and the appropriate therapeutic treatment of somatostatin analogs did not lead to normalization of concentrations of insulin growth factor-1 (IFR-1) or postponed patients contract services . renal insufficiency, the recommended dose is 0.045 mh/kh-0, 050 mg / kg (approximately 0.14 IU / kg) of body weight per day in contract services subcutaneously injection; children born too small for gestational age recommended dose is 0.067 mg / kg body weight per day in a subcutaneously injection; undersized patients without growth hormone deficiency is recommended to use a one-week here 0.37 mg / kg body weight in a subcutaneously injection, the dose should be divided into equal doses 3 - 7 times a week to patients with SHOX-failure recommended dose of 0.35 mg / kg of body weight dose should be divided into equal parts and be entered in a daily subcutaneously injection, in patients with excessive body weight are more prone to developing side effects when contract services is based on the selection of doses depending on body weight, women with high estrogen levels may require higher doses than men, oral estrogens may require increased doses in women, usually recommended daily subcutaneously injections do in the evening, here are general guidance on dose - when growth disorder due to insufficient secretion of growth hormone in children recommended dose is 0,07-0,10 IU / kg (0,025-0,035 mg / kg) per day or 0,7-1,0 mg / m2 body surface area Hematopoietic Cell Transplantation MO/m2) a day for treatment of growth at S-E-Turner Shereshevsky and XP. similar to thyroid stimulating hormone; tyreotropin-alpha (rekombinant hormone, thyroid-stimulating human) is a hetero-dimeric glycoprotein, produced by technology rekombinantiv DNA consists of two linked parts nekovalentno; compounds c-DNA coding for performing part of " alpha "of 92 amino acids containing two-glycopolymers sylatsiyni cells connected N-connection, and part of a" beta "of 118 residues containing one glycopolymers sylatsiynyy-center, N-linked bond , it has very similar biochemical properties of natural human hormone that stimulates the thyroid gland (TSH); fixing tyreotropinu-alpha receptors on TSH-thyroid epithelial cells promotes the absorption of iodine and transfer it into an organic form, and thyroglobulin synthesis and release, contract services (T3) contract services thyroxine (T4) in the application of alpha-tyreotropinu 0.9 mg TSH stimulation of hormones needed for diagnostic procedures, achieved against a background therapy, which provides normal thyroid function, reducing the level of thyroid hormone, thus avoiding symptoms related to deficiency of thyroid function. patient's condition because of complications after surgery for open heart or abdominal surgery, multiple traumatic injuries or if the patient until the hour.
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