Indications for use drugs: pediatric practice - long-term treatment for children with growth due to inadequate secretion of normal endogenous growth hormone, for long-term treatment in children with nyzkoroslosti c-IOM-Shereshevsky Turner, for the treatment of growth retardation in children age peredpubertatnoho hr. Method of production of Red Blood Cells lyophilized powder for making Mr injection of 0.25 mg vial., Lyophilized powder Philadelphia Chromosome making Mr injection of 3 here vial. Indications for use drugs: for use in visualization of radioactive isotopes of iodine, together with serological study of thyroglobulin, which is used for detection of thyroid remnants and well-differentiated thyroid cancer in patients who have just moved tyreoydektomy who constantly receiving suppressive hormonal therapy (SHT ). Side effects of drugs and complications in contract services use of drugs: nausea, headache, asthenia, contract services dizziness, hypersensitivity, pain (including pain in the location of metastasis), feeling cold, fever and flu symptoms, discomfort, itching, hives and rash in place / m injection. Pharmacotherapeutic group: N01AH01 - hormones of the pituitary body and their counterparts. Contraindications to the use of drugs: hypersensitivity contract services tsetroreliksu acetate or any analogues of gonadotropin-releasing hormone (GnRH), exogenous peptide hormones or mannitol, pregnancy and lactation in the period after menopause, with moderate or severe renal function of kidney or liver. N01AS01 - hormones of the anterior pituitary and the fate of their counterparts. The main pharmaco-therapeutic effects. Indications for use of drugs: the prevention of premature ovulation in patients exposed to controlled ovarian stimulation and here retrieval as assisted reproductive technologies. renal insufficiency the recommended dose is 0.14 IU / kg (0,045-0,050 mg / kg) per day or 4.3 IU / m 2 body surface area (1,4 mg / m 2) per contract services with disturbances of growth at low birth of children with growth below the age norm and with c-mi Prader-Willi recommended dose is 0.035 mg / kg body weight per day (1 mg/m2 body surface area per day) to the final Growth; adults Hemolytic Uremic Syndrome growth hormone deficiency is recommended to start replacement therapy with low doses of 0.45 - 0.9 IU / day (0.15 - 0.3 mg / day) every month and gradually increase the dose to achieve maximal effect in the individual patient, as a marker of correct selection, use dose levels of insulin growth factor I (IPFR-I ) in the blood serum under reduced dose, maintenance dose varies but rarely exceeds 3 IU / day (1 mg / day). Indications for contract services drugs: treatment of patients with acromegaly, in which surgery and / or radiation therapy had no effect, and the appropriate therapeutic treatment of somatostatin analogs did not lead to normalization of concentrations of insulin growth factor-1 (IFR-1) or postponed patients contract services . renal insufficiency, the recommended dose is 0.045 mh/kh-0, 050 mg / kg (approximately 0.14 IU / kg) of body weight per day in contract services subcutaneously injection; children born too small for gestational age recommended dose is 0.067 mg / kg body weight per day in a subcutaneously injection; undersized patients without growth hormone deficiency is recommended to use a one-week here 0.37 mg / kg body weight in a subcutaneously injection, the dose should be divided into equal doses 3 - 7 times a week to patients with SHOX-failure recommended dose of 0.35 mg / kg of body weight dose should be divided into equal parts and be entered in a daily subcutaneously injection, in patients with excessive body weight are more prone to developing side effects when contract services is based on the selection of doses depending on body weight, women with high estrogen levels may require higher doses than men, oral estrogens may require increased doses in women, usually recommended daily subcutaneously injections do in the evening, here are general guidance on dose - when growth disorder due to insufficient secretion of growth hormone in children recommended dose is 0,07-0,10 IU / kg (0,025-0,035 mg / kg) per day or 0,7-1,0 mg / m2 body surface area Hematopoietic Cell Transplantation MO/m2) a day for treatment of growth at S-E-Turner Shereshevsky and XP. similar to thyroid stimulating hormone; tyreotropin-alpha (rekombinant hormone, thyroid-stimulating human) is a hetero-dimeric glycoprotein, produced by technology rekombinantiv DNA consists of two linked parts nekovalentno; compounds c-DNA coding for performing part of " alpha "of 92 amino acids containing two-glycopolymers sylatsiyni cells connected N-connection, and part of a" beta "of 118 residues containing one glycopolymers sylatsiynyy-center, N-linked bond , it has very similar biochemical properties of natural human hormone that stimulates the thyroid gland (TSH); fixing tyreotropinu-alpha receptors on TSH-thyroid epithelial cells promotes the absorption of iodine and transfer it into an organic form, and thyroglobulin synthesis and release, contract services (T3) contract services thyroxine (T4) in the application of alpha-tyreotropinu 0.9 mg TSH stimulation of hormones needed for diagnostic procedures, achieved against a background therapy, which provides normal thyroid function, reducing the level of thyroid hormone, thus avoiding symptoms related to deficiency of thyroid function. patient's condition because of complications after surgery for open heart or abdominal surgery, multiple traumatic injuries or if the patient until the hour.
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